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Antimicrobial Drug Discovery

Call for Papers

Reports of hospital ward closures and multidrug resistance bacterial outbreaks/infections continue to make headline news. Even our last resort drugs for multiresistant pathogens such as methicillin-resistant Staphylococcus aureus (MRSA) seem increasingly fallible. The development of drug resistance in other infectious organisms is also a growing problem. After more than 50 years, natural sources of antibiotics (and anti-infectives) seem to be exhausted, and it is becoming increasingly difficult to deliver new leads based on chemical modification of the known antibiotic scaffolds.

Despite the wealth of biological data generated with the advent of molecular, computational, cellular, and biophysical technologies and its application to the discovery and development of new antimicrobials, the number of new drugs that arrive to the market is very limited.

We invite authors to submit original research and review articles that allow us to understand the mechanism of antibiotic resistance and discover potential new targets. The invitation is extended to those investigators seeking to apply the actual knowledge in order to provide new antimicrobials or alternative strategies in drug discovery and design. Potential topics include, but are not limited to:

  • New antimicrobials from nature
  • Alternative strategies to treat or prevent microbial infections
  • Novel targets for antimicrobial development
  • Novel resistance mechanisms
  • Structure-based drug design of novel antimicrobials
  • Target-based drug discovery
  • Antimicrobial microbes and viruses
  • Antimicrobial mechanism of action

Before submission authors should carefully read over the journal’s Author Guidelines which are located at http://www.hindawi.com/journals/bmri/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/bmri/biochemistry/adis/ according to the following timetable:

Manuscript DueFriday, 13 June 2014
First Round of ReviewsFriday, 5 September 2014
Publication DateFriday, 31 October 2014

Lead Guest Editor

  • Alberto Marina, Department of Genomics and Proteomics, Institute of Biomedicine of Valencia (IBV), Spanish National Research Council (CSIC), Valencia, Spain

Guest Editors

  • Jerry Wells, Host Microbe Interactomics Group at Wageningen University, Wageningen, The Netherlands
  • Teresa Pellicer, R&D Department Interquim, Grupo Ferrer, Barcelona, Spain
  • Paul Finn, Applied Computing Department, The University of Buckingham, Buckingham, United Kingdom