Endometriosis: Novel Models, Diagnosis, and Treatment
1Pelvic Endoscopy and Minimally Invasive Gynecological Surgery Unit, Policlinico Universitario S.Orsola-Malpighi, Via Massarenti 13, Bologna, Italy
2Department of Obstetrics and Gynecology, Sacred Heart Hospital, Negrar, Verona, Italy
3Department of Obstetrics and Gynecology, American University of Beirut Medical Center, Beirut, Lebanon
Endometriosis: Novel Models, Diagnosis, and Treatment
Description
Endometriosis remains a cause of significant morbidity in reproductive-aged women resulting in pelvic pain, pelvic masses, and infertility. Endometriosis is defined as the presence of endometrial glands and stroma outside of their normal intrauterine location, most commonly in the dependent portions of the pelvis. Endometriosis is treated with medical therapies, surgery, or both. The medical therapies include oral contraceptive pills, progestins, gonadotropin releasing hormone analogues, and danazol. All of these medical therapies induce a hormonal steady state that results in an environment not conducive to the growth of endometriosis. Surgical therapies for endometriosis-associated pain include the removal of endometriotic implants and adhesions with restoration of normal anatomy. Laparoscopy is an effective surgical approach with the goal of excising visible endometriosis. Since endometriosis is a chronic condition, it is not uncommon for recurrences to occur. While endometriosis remains an enigmatic disease, the introduction of new pharmacologic agents and newer endoscopic methods of surgical treatment has facilitated and improved the overall management of this disease.
We invite investigators worldwide to contribute original articles and reviews that contribute to the advancement of endometriosis treatment research. Investigators are particularly encouraged to report the state of research in endometriosis surgical treatment, progress in the understanding of basic molecular mechanisms of this disease, and the development of novel biomarkers and therapeutic agents. Potential topics include, but are not limited to:
- Molecular and cellular mechanisms of endometriosis physiopathology
- Biomarker development for improved early diagnosis and risk of disease
- Minimally invasive treatment for endometriosis
- New medical therapies
- Prevention of endometriosis and identification of adolescent at risk of developing endometriosis
- Novel models in endometriosis research
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