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Genomics and Epigenomics of Cardiovascular and Metabolic Disorders in Human

Call for Papers

High-throughput technologies have led to a revolution in our ability to explore the genomic and epigenomic mechanisms underlying complex traits and diseases, such as adiposity, type-2 diabetes, and cardiovascular disease. Methodological opportunities and analytic strategies are complex and rapidly evolving and yield extensive computational challenges. Increasing sample size, made possible through global collaborative networks, is yielding extensive new mechanistic insight. Translating these findings to clinical benefit is a major challenge.

The main focus of this special issue will be on the new and existing population research studies whose goal is to investigate the genomic and epigenomic mechanisms underlying complex traits and diseases in humans. The special issue will become an international forum for researchers to summarize the most recent developments and ideas in the field, with a special emphasis given to the technical and observational results obtained within the last five years. Potential topics include, but are not limited to:

  • Genetic mechanisms
  • Epigenetic mechanisms
  • Analytic and methodological approaches
  • Analysis pipelines
  • Genetics and epigenetics of complex traits
  • Population studies
  • Cross-omic approaches
  • Clinical translation
  • Diagnosis, risk stratification, and therapeutics
  • Future strategies

Before submission authors should carefully read over the journal’s Author Guidelines, which are located at http://www.hindawi.com/journals/bmri/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/bmri/genetics/gp/ according to the following timetable:

Manuscript DueFriday, 12 December 2014
First Round of ReviewsFriday, 6 March 2015
Publication DateFriday, 1 May 2015

Lead Guest Editor

  • John C. Chambers, Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG, UK

Guest Editors

  • Tonu Esko, Estonian Genome Center, University of Tartu, Riia 23c, 51010 Tartu, Estonia
  • Pim van der Harst, Department of Cardiology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
  • Jaspal S. Kooner, Imperial College London, London W12 0NN, UK