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Brain Metastasis and Radiation Toxicity

Call for Papers

Brain metastasis is an unfortunate diagnosis that affects approximately 200,000 Americans a year. Until recently, whole brain radiation with or without surgical resection has been the standard of care for patients with single brain metastasis and whole brain radiation alone for patients with multiple metastases. However, it has been recognized that cancer therapy can indeed result in negative effects on neurocognition. This can include surgery and chemotherapy, but especially whole brain radiation. There have been very recent technological and pharmaceutical advances that have impacted our ability to mitigate this devastating complication of cancer therapy for brain metastasis

In this special issue, we invite investigators to provide review articles and original research that will continue to stimulate discussion and potential practice enhancing insights to help reduce the toxicity of therapy for brain metastasis. Potential topics include, but are not limited to:

  • Overview of brain metastasis management
  • Biology of neurocognitive decline from radiation, surgery, and chemotherapy
  • Novel radiation techniques, such as hippocampal sparing whole brain radiation, for the prevention of neurocognitive decline
  • Neurocognitive decline from radiosurgery versus whole brain radiation
  • Role of chemoprevention to prevent neurocognitive decline in patients with brain metastasis
  • Personalizing cancer therapy for reducing neurocognitive decline
  • Imaging changes after cancer therapy
  • Review of radiation necrosis
  • Treatments for radiation toxicity (e.g., radiation necrosis, neurocognitive decline)
  • Future strategies to limit neurocognitive decline
  • Radiation toxicity related to radiosurgery, proton therapy, and/or brachytherapy

Before submission authors should carefully read over the journal’s Author Guidelines, which are located at http://www.hindawi.com/journals/bmri/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/bmri/neurology/bmrt/ according to the following timetable:

Manuscript DueFriday, 27 June 2014
First Round of ReviewsFriday, 19 September 2014
Publication DateFriday, 14 November 2014

Lead Guest Editor

  • Deepak Khuntia, Varian Medical Systems and The Targeted Radiation Institute of VMOC, Palo Alto, CA 94034, USA

Guest Editors

  • Paul Brown, Department of Radiation Oncology, MD Anderson Cancer Center, Houston, TX 77030, USA
  • Vinai Gondi, Department of Radiation Oncology, Cadence Brain Tumor Center and Proton Center, Warrenville, IL 60126, USA
  • John Suh, Department of Radiation Oncology, Cleveland Clinic Foundation, Cleveland, OH 44195, USA