Insulin Blocks Glutamate-Induced Neurotoxicity in Differentiated SH-SY5Y Neuronal Cells

<table class="table-group" id="tab1"><tr><td><table class="table"><tr><td class="thead-hr" colspan="2"><hr/></td></tr><tr class="thead"><td align="left">Treatment</td><td align="center">Percentage cell viability</td></tr><tr><td class="thead-hr" colspan="2"><hr/></td></tr><tr><td align="left">Control</td><td align="center">100.00 ± 0.012</td></tr><tr><td align="left">Insulin (0.01 <i>μ</i>M)</td><td align="center">110.66 ± 7.2</td></tr><tr><td align="left">Insulin (0.1 <i>μ</i>M)</td><td align="center">149.09 ± 17.0</td></tr><tr><td align="left">Insulin (1 <i>μ</i>M)</td><td align="center">165.83 ± 10.0*</td></tr><tr><td align="left">Insulin (10 <i>μ</i>M)</td><td align="center">139.67 ± 14.3</td></tr><tr class="table-tr"><td colspan="2"><hr class="tbody-hr"/></td></tr></table></td></tr><tr class="table-fn"><td>
                Values are expressed as mean ± SEM of three tests in triplicate. Statistical analysis was done by using one-way ANOVA followed by Tukey’s multiple comparison test. *<i>P</i> &lt; 0.05 compared to control group.<br/></td></tr></table>

Effect of treatments on cell viability in differentiated SH-SY5Y cells.

Behavioural Neurology

tab1

Table 1

Table 1: Insulin Blocks Glutamate-Induced Neurotoxicity in Differentiated SH-SY5Y Neuronal Cells 