Modulatory Role of Simvastatin against Aluminium Chloride-Induced Behavioural and Biochemical Changes in Rats

Table 1

Effect of simvastatin on serum lipid profile.

Treatment	Total cholesterol	Triglycerides	LDL	HDL
	(mg/dL)	(mg/dL)	(mg/dL)	(mg/dL)
Normal control	68.63 ± 2.77	66.67 ± 1.93	21.15 ± 2.27	43.03 ± 1.10
Vehicle control	62.25 ± 4.36	65.21 ± 3.36	19.95 ± 2.19	44.65 ± 1.48
AlCl3	90.19 ± 3.22^*	110.9 ± 9.85^*	31.81 ± 2.78^*	30.19 ± 0.98^*
AlCl3 + rivastigmine	72.91 ± 3.99	72.45 ± 7.58	22.21 ± 3.17	31.68 ± 2.00
AlCl3 + simvastatin	55.12 ± 3.54^#	60.81 ± 2.04^#	11.76 ± 2.37^#	42.12 ± 3.27^#

Effect of AlCl₃ and AlCl₃ + treatments on (a) total cholesterol, (b) triglycerides, (c) LDL, and (d) HDL. Data are presented as mean ± SEM ( = 8). as compared to control group and as compared to AlCl₃ treated group.