Cox-2 Plays a Vital Role in the Impaired Anxiety Like Behavior in Colchicine Induced Rat Model of Alzheimer Disease

Figure 5

The frequency of approach to the object area in an elevated open space with a novel object (for anxiety status) of different experimental groups of rats. versus control/sham operated rats at day 14 (). versus control/sham operated rats at day 21 (). versus etoricoxib treated cAD at all the doses at day 14 (), versus etoricoxib treated cAD at all the doses at day 21 (), and  mg/kg body weight etoricoxib administered cAD versus 30 mg/kg body weight etoricoxib administered cAD at day 14 (). Abbreviations are the same as in Figure 1. Values are expressed in mean ± SEM ( in each group).