Mice with Catalytically Inactive Cathepsin A Display Neurobehavioral Alterations

Figure 1

mice 3, 6, and 12 months old performed significantly worse than their aged-matched wild-type littermates in a passive avoidance task. Latencies to enter the dark compartment on the test day are shown. If mice did not enter the dark compartment within 600 s, a latency time of 600 s was recorded. The data are presented as the mean ± standard error of the mean (SEM); .