Research Article

Spatial Navigation Impairment Is Associated with Alterations in Subcortical Intrinsic Activity in Mild Cognitive Impairment: A Resting-State fMRI Study

Table 3

Correlations between ReHo and spatial navigation accuracy in the right thalamus, hippocampus, pallidum, and amygdala.

Navigation accuracyR thalamusR pallidumR hippoR amygdala
r/Fr/Fr/Fr/F

Allo-EgoWithin MCI0.390.110.430.070.290.240.270.28
Within NC−0.350.17−0.260.31−0.330.19−0.350.17
Interaction3.040.091.510.233.220.082.490.12

EgoWithin MCI−0.120.630.400.100.210.400.170.50
Within NC−0.030.90−0.040.86−0.170.50−0.230.38
Interaction0.210.641.000.321.090.301.710.20

AlloWithin MCI0.210.410.320.200.180.460.190.44
Within NC−0.490.05−0.500.04−0.450.07−0.380.13
Interaction5.950.028.970.014.440.042.820.10

For “within MCI” and “within NC” rows, the r/F columns, the “r” (correlation coefficients) represents the correlation between ReHo and respective SN total distance error. For “interaction” rows, the value represents the effect of clinical diagnosis (MCI or NC) on this correlation. .