Effects of Ficus umbellata (Moraceae) Aqueous Extract and 7-Methoxycoumarin on Scopolamine-Induced Spatial Memory Impairment in Ovariectomized Wistar Rats

Figure 6

Graphic representation of the number of rearing (a and b) and grooming (c and d) of rats in the Y-maze before and after scopolamine exposition in rats treated with different substances into the Y-maze. SHAM 1 = sham-operated rats treated with vehicle as normal control 1; SHAM 2 = sham-operated rats treated with vehicle as normal control 2; OVX = ovariectomized rats treated with vehicle as negative control; PIR = ovariectomized rats treated with piracetam at the dose of 1.5 mg/kg BW as positive control 1; E2V = ovariectomized rats treated with estradiol valerate at the dose of 1 mg/kg BW as positive control 2; FU 50 and 200 = ovariectomized rats treated with F. umbellata aqueous extract at the doses of 50 and 200 mg/kg BW, respectively; MC = ovariectomized rats treated with 7-methoxycoumarin at the dose of 1 mg/kg BW. SCOP = animal that received a single dose of scopolamine (2 mg/kg BW). and as compared to the SHAM 1 group; and as compared to the SHAM 2 group; , , and as compared to the OVX group.

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