Comparing Sensitivity and Specificity of Addenbrooke’s Cognitive Examination-I, III and Mini-Addenbrooke’s Cognitive Examination in Parkinson’s Disease

Table 2

Diagnostic accuracy of ACE-I, ACE-III, Mini-ACE, and MMSE for detecting mild neurocognitive disorder in the respect of education years.

Mild neurocognitive disorder		Best cut-off score	Sensitivity	Specificity	Youden’s index	Positive likelihood ratio	Negative likelihood ratio	AUC area
ACE-I	0–8	84.5	0.862	0.571	0.433	2.011	0.241	0.713
	9–12	86.5	0.850	0.614	0.464	2.204	0.244	0.787
	>12	90.5	0.847	0.626	0.473	2.263	0.244	0.819
ACE-III	0–8	83.5	0.931	0.643	0.574	2.607	0.107	0.733
	9–12	85.5	0.805	0.786	0.511	2.917	0.477	0.771
	>12	88.5	0.765	0.744	0.509	2.985	0.316	0.838
Mini-ACE	0–8	23.5	0.793	0.714	0.507	2.776	0.290	0.749
	9–12	24.5	0.850	0.514	0.364	1.750	0.292	0.746
	>12	25.5	0.718	0.798	0.516	3.553	0.354	0.820
MMSE	0–8	26.5	0.414	0.857	0.271	2.897	0.684	0.602
	9–12	27.5	0.575	0.743	0.318	2.236	0.572	0.723
	>12	28.5	0.612	0.714	0.326	2.141	0.544	0.696