Gait and Conditioned Fear Impairments in a Mouse Model of Comorbid TBI and PTSD

Figure 2

Gait metrics after TBI + PTSD. (a) Experimental design and diagram of the mouse gait representing a step cycle and stance width measures. (b) Stance width in fore and hind limbs. Forelimb stance width was decreased in TBI + PTSD mice compared to TBI alone () and controls (). (c) Paw overlap in left and right sides. Paw placement in the left side of TBI + PTSD mice was significantly increased compared to TBI alone mice (). (d) Stance duration in each paw. Stance duration in the left hind limbs was significant in the omnibus ANOVA (), and post hoc testing was trending in TBI + PTSD relative to control and TBI alone mice. Error bars ± SEM, .

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