A Randomized Clinical Trial of a Functional Electrical Stimulation Mimic to Gait Promotes Motor Recovery and Brain Remodeling in Acute Stroke

Figure 2

Representative brain remodeling with three subjects. (a), (c), (e), and (g) show T1WI, T2W2, FA, DTT, respectively, before intervention. (b), (d), (f), and (h) show T1WI, T2W2, FA, and DTT, respectively, after intervention. In all the three groups, pictures (b) and (d) suggest that perilesional edema was absorbed obviously after intervention; pictures (e) and (g) suggest that the bundle of fibers in lesional regions was significantly less than contralateral side and it was interrupted, compressed, and shifted. In the four-channel group, pictures (f) and (h) suggest that fibers in the same lesional regions increased significantly after treatment. In the dual-channel group, pictures (f) and (h) suggest that fibers in lesional regions do not increase but even decreased after treatment. Fibers seem to increase in the contralateral regions. In the placebo group, pictures (f) and (h) suggest that fibers in the lesional regions do not increase after treatment. We took the samples as follows: a patient, male, 62 years old, with left parietal lobe hematoma for the four-channel group; a patient, male, 52 years old, with right ganglia and corona radiata infarction for the dual-channel group; and a patient, male, 62 years old, with left parietal lobe hematoma for the placebo group.