Research Article

Medication Belief and Adherence among Patients with Epilepsy

Table 5

Factors associated with medication adherence among epileptic patients ().

PredictorsMedication adherenceCOR (95% CI) valueAOR (95% CI) value
Adherent, n (%)Nonadherent, n (%)

Age in years
 18-3060 (59.4)112 (58.6)1111
 31-6036 (35.6)76 (39.8)0.99 (0.60-1.64)0.9711.83 (0.91-3.69)0.090
 >605 (5.0)3 (1.6)0.305 (0.07-1.32)0.1130.62 (0.07-5.55)0.671
Social drug use
 No92 (91.1)157 (82.2)1111
 Yes9 (8.9)34 (17.8)2.21 (1.02-4.82)0.0450.79 (0.26-2.40)0.672
Comorbidity
 No85 (84.2)93 (48.7)1111
 Yes16 (15.8)98 (51.3)5.60 (3.06-10.25)<0.0013.51 (1.20-10.31)0.022
Types of seizure
 GTC72 (71.3)143 (74.9)1111
 Focal seizure14 (13.9)28 (14.7)1.85 (0.85-4.05)0.1220.43 (0.16-1.16)0.096
 Absence seizure1 (1.0)5 (2.6)1.87 (0.71-4.93)0.2080.72 (0.04-13.54)0.823
 Unclassified seizure14 (13.9)28 (14.7)4.67 (0.48-45.04)0.1830.57 (0.21-1.55)0.272
Number of medications
 <362 (61.4)80 (41.9)1111
 ≥339 (38.6)111 (58.1)2.21 (1.35-3.61)0.0020.53 (0.21-1.36)0.185
Seizure encounter
 No88 (87.1)71 (37.2)
 Yes13 (12.9)120 (62.8)11.44 (5.96-21.96)<0.0015.45 (2.48-12.00)<0.001
Medication necessity belief
 High necessity91 (90.1)138 (72.3)1111
 Low necessity10 (9.9)53 (27.7)6.74 (2.80-16.26)<0.0013.38 (1.14-10.00)0.028
Medication concern belief
 Strong concern17 (16.8)112 (58.6)7.00 (3.86-12.71)<0.0014.23 (2.07-8.63)<0.001
 Low concern84 (83.2)79 (41.4)1111
Over all medication belief
 Negative belief11 (10.9)104 (54.5)9.78 (4.92-19.46)<0.0014.17 (1.74-10.02)0.001
 Positive belief90 (89.1)87 (45.5)1111

COR: crude odds ratio; AOD: adjusted odds ratio; CI: confidence interval; GTC: generalized tonic seizure.