Function of Membrane Rafts in Viral Lifecycles and Host Cellular Response

Table 2

Function of membrane rafts in enveloped RNA viruses.

Family	Virus	Process
Arenaviridae	Lymphocytic choriomeningitis virus; (LCMV)	Entry
Coronaviridae	SARS-CoV, coronavirus	Entry; Lung pathogenicity
Filoviridae	Ebola virus	Entry; Fusion; Assembly; Budding
	Marburg virus	Entry; Budding
Flaviviridae	Dengue virus; (DEN)	Entry; Viral RNA replication; ADE of viral infection; Antiapoptosis; Pathogenicity
	Japanese encephalitis virus; (JEV)	Entry; Viral RNA replication; Progeny virus; production; Anti-apoptosis; Neuronal pathogenicity
	West Nile virus; (WNV)	Entry; Basolateral transportation; in endothelial cells; Viral spreads from the blood; stream to the central nervous; system and peripheral tissues
	Human hepatitis C virus; (HCV)	Entry; Vrial RNA replication; Progeny virus infectivity; Budding; MoDC maturation; Viral immune evasion; Persistent infection
Orthomyxoviridae	Influenza virus	Fusion; Assembly; Budding; Progeny virus infectivity; Apical targeting; Viral proton channel
Paramyxoviridae	Measles virus	Assembly; Inflammatory response; Immunosuppression
	Newcastle disease virus; (NDV)	Assembly; Budding; Progeny virus infectivity
	Respiratory syncytial virus; (RSV)	Viral RNA replication; Assembly; Budding; Host immune response
	Sendai virus	Assembly
Retroviridae	Human immunodeficiency virus; (HIV)	Entry; Assembly; Budding; Release; Progeny virus production; Viral nephropathy; Persistent infection in macrophages
	Human T lymphotropic virus 1; (HTLV-1)	Entry; Fusion; Assembly; T cell leukemia
Rhabdoviridae	Vesicular stomatitis virus; (VSV)	Budding
Togaviridae	Semliki forest virus; Sindbis virus	Fusion; Entry