ER Stress and Iron Homeostasis: A New Frontier for the UPR

Figure 1

CRT expression and HH-related symptoms. CRT mRNA expression in PBMCs from HFE C282Y homozygous patients. Each bar represents an individual subject, ordered by CRT level and divided according to the presence (light blue bars) or absence (dark blue bars) of cirrhosis/fibrosis (CIRR/FIB), modified by Porto from original data from Pinto et al., 2008 [59].