The Increased Activity of Liver Lysosomal Lipase in Nonalcoholic Fatty Liver Disease Contributes to the Development of Hepatic Insulin Resistance

Figure 3

The effect of HFD on the LIPA protein expression. (a) Homogenate; (b) dense lysosomes; (c) light lysosomes. Representative Western blots are shown above each graph (f  = fasted, F  = fed). The results are expressed as arbitrary units after normalisation to the actin expression (loading control). Open bars  = fasted animals; hatched bars  = fed animals. ⁺⁺𝑃<0.01 fed versus fasted; ^##𝑃<0.01 HFD fed versus SD fed.

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