Research Article

Length and PKA Dependence of Force Generation and Loaded Shortening in Porcine Cardiac Myocytes

Figure 2

(a) Pig cardiac myocyte sarcomere length-tension relationships before and after PKA treatment. PKA-induced phosphorylation markedly steepened the length-tension relationship. (b) An autoradiogram showing radiolabeled phosphate incorporation into pig cardiac myofibrillar proteins (MyBP-C and cTnI) upon PKA treatment. Without PKA treatment, there was no radiolabelled ATP incorporation (data not shown).
371415.fig.002