Length and PKA Dependence of Force Generation and Loaded Shortening in Porcine Cardiac Myocytes

Figure 4

Normalized force-velocity and power-load curves from a pig left ventricular myocyte preparation at long and short sarcomere length obtained during half-maximal Ca²⁺ activations. Pig cardiac myocyte preparations exhibited little sarcomere length dependence of loaded shortening and power output. Inset shows bar plot (mean ± SD) of peak normalized power output at long (~2.30 μm) and short (~1.90 μm) sarcomere length (𝑛=8 myocyte preparations).