Caveolin 3, Flotillin 1 and Influenza Virus Hemagglutinin Reside in Distinct Domains on the Sarcolemma of Skeletal Myofibers
Figure 4
Cholesterol depletion destroys the morphology of caveolae. (a) In an intact FDB myofiber, there are abundantly flask-shaped caveolae that form rosettes (marked by arrowheads) beneath the sarcolemma. (b) Treatment with 1 mM CDX reduces the number of caveolae, and the morphology of individual caveolae (arrowheads) is distorted. (c) Treatment with 5 mM CDX results in flattened caveolae without any distinguishable morphology. Scale bar, 500 nm.
