Association of TCTP with Centrosome and Microtubules

Figure 2

Expression of Myc-XlTCTP in Xenopus laevis XL2 cells. (a) Confocal section of XL2 cell in anaphase with high concentration of XlTCTP at the spindle poles (white arrows). (b) Confocal section of two dividing XL2 cells with high concentration of XlTCTP at the spindle poles. (c) Control mitotic XL2 cells expressing Myc tag only. (d) Interphase XL2 cell expressing Myc-XlTCTP. XLTCTP is localized in distinct fibers in the cytoplasm. (e) Mitotic murine NIHT3T cell expressing Myc-XlTCTP. High concentration of XlTCTP is present at the spindle poles (white arrows). (f) Interphase murine NIH3T3 cells expressing Myc-XlTCTP. Note that XlTCTP forms MT-like fibers in the cytoplasm. Bar is equal to 20 μm.