Research Article

Effect of Vitamins A, C, and E Supplementation in the Treatment of Metabolic Syndrome in Albino Rats

Table 3

Effect of antioxidant supplementation on antioxidant indices and lipid peroxidation.

GroupVitamin C Vitamin E TAS MDA
(mg/dL)(mg/dL)(mmol/L)(nmoL/mg tissue)

I0.95 ± 0.150.73 ± 0.321.64 ± 0.240.382 ± 0.04
II0.51 ± 0.05c0.47 ± 0.010.70 ± 0.17c1.210 ± 0.22c
III0.74 ± 0.17b,d0.63 ± 0.061.33 ± 0.27a0.402 ± 0.08a
IV0.66 ± 0.03c0.63 ± 0.051.16 ± 0.22b,d0.425 ± 0.22a
V0.74 ± 0.08b0.77 ± 0.15b1.33 ± 0.28a0.423 ± 0.10a
VI0.81 ± 0.17a0.78 ± 0.12b1.42 ± 0.34a0.432 ± 0.06a

TAS-total antioxidant status, MDA-malondialdehyde, I: normotensive control, II: hypertensive control, III: group treated with vit C, IV: group treated with vit A, V: group treated with vit E, and VI: group treated with all the vitamins. Values are expressed as mean ± SD; . aP < 0.01 when compared with group II, bP < 0.05 when compared with group II, cP < 0.01 when compared with group I, and dP < 0.05 when compared with group I by Dunnette’s multiple comparison test.