789083.fig.002a
(a)
789083.fig.002b
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Figure 2: Dendrite reshaping in Drosophila sensory neurons is mediated by matrix metalloproteinases. (a) Dendritic pattern of a single class IV neurons in 0 hr and 72 hr posteclosion adults. (b) Dendrites of Drosophila sensory neurons are rapidly reshaped within 24 hours after eclosion. This dendrite reshaping is promoted by the matrix metalloproteinase Mmp2-mediated degradation of the basement membrane, suggesting that proteolytic alteration of the extracellular matrix plays a fundamental role in remodeling of dendritic structures during reorganization of neuronal circuits. This model is predominantly based on data from [15].