Table 2: Genes associated with hypertrophic cardiomyopathy.

GeneProteinFunctionReference

β-MHCβ-Myosin heavy chainSarcomere protein[5]
α-MHCα-Myosin heavy chainSarcomere protein[6, 7]
cMYBPCCardiac myosin-binding protein CSarcomere protein[8, 9]
cTnICardiac troponin ISarcomere protein[10]
cTnTCardiac troponin TSarcomere protein[11]
cTnCCardiac troponin CSarcomere protein[12]
α-TMα-TropomyosinSarcomere protein[11]
MLC-1Myosin essential light chainSarcomere protein[13]
MLC-2Myosin regulatory light chainSarcomere protein[7]
ACTCActinSarcomere protein[14]
TTNTitinSarcomere protein[15, 16]

Metabolic phenocopies
PRKAG2AMP kinase[17]
LAMP2Lysosome membrane protein[18]