Table 3: Genes associated with dilated cardiomyopathy.

GeneProteinFunctionReference

Autosomal dominant
ACTCCardiac actinSarcomere protein[19]
DESDesminDystrophin-associated glycoprotein complex[20]
SGCDδ-SarcoglycanDystrophin-associated glycoprotein complex[21]
MYH7β-Myosin heavy chainSarcomere protein[22, 23]
TNNT2Cardiac troponin TSarcomere protein[22, 24, 25]
TPM1α-TropomyosinSarcomere protein[26]
TTNTitinSarcomere structure[27]
VCLMetavinculinIntercalated discs[28]
MYBPCMyosin-binding protein CSarcomere protein[23]
MLP/CSRP3Muscle LIM proteinZ discs[29]
ACTN2α-Actinin-2Sarcomere structure[30]
MYH6α-Myosin heavy chainSarcomere protein[31]
ABCCSUR2ACardiac K channel[32]
LMNALamin A/CNuclear membrane protein[33]
PLNPhospholambanSarcoplasmic reticulum Ca regulator[34, 35]
ZASP/LBD3CypherCytoskeletal assembly[36]

X linked
DMDDystrophinDystrophin-associated glycoprotein complex[37, 38]
TAZ/G4.5Tafazzin[39, 40]

Recessive
TNNI3Troponin ISarcomere protein[41]