A Quantitative Structure-Activity Relationship and Molecular Modeling Study on a Series of Heteroaryl- and Heterocyclyl-Substituted Imidazo[1,2-a]Pyridine Derivatives Acting as Acid Pump Antagonists
Figure 4
The model showing hydrophobic interactions of predicted compound 2 (Table 2) with the enzyme H+/K+-ATPase. The red surface shows strong hydrophobic zone and blue one the low hydrophobic zone.