Research Article
Escin Chemosensitizes Human Pancreatic Cancer Cells and Inhibits the Nuclear Factor-kappaB Signaling Pathway
Table 1
Analysis of a mode of combined treatment with Escin + gemcitabine or Escin + cisplatin.
| Escin (µM) | Gemcitabine (nM) | Combination index (CI) | Escin (µM) | Cisplatin (µM) | Combination index (CI) |
| 2 | 3 | 2.07 | 5 | 0.3 | 1.30 | 5 | 3 | 1.06 | 10 | 0.3 | 0.78 | 10 | 3 | 1.04 | 15 | 0.3 | 0.82 | 2 | 10 | 0.97 | 5 | 1 | 1.68 | 5 | 10 | 0.98 | 10 | 1 | 0.81 | 10 | 10 | 0.98 | 15 | 1 | 0.27 | 2 | 30 | 1.25 | 5 | 3 | 0.45 | 5 | 30 | 1.17 | 10 | 3 | 0.26 | 10 | 30 | 0.98 | 15 | 3 | 0.19 |
|
|