Review Article

C-Lobe of Lactoferrin: The Whole Story of the Half-Molecule

Figure 5

A comparison of the (a) C-lobe of intact lactoferrin and (b) C-lobe which has been cleaved from the intact lactoferrin using proteinase K. Apart from one single cut at the N-terminus, the enzyme cleaves the C-terminal part of the protein at three points, leading to the generation of a pentapeptide which is anchored to the main protein by a disulfide bond between C405 and C684.
271641.fig.005a
(a)
271641.fig.005b
(b)