miR-149 Inhibits Non-Small-Cell Lung Cancer Cells EMT by Targeting FOXM1

Figure 1

miR-149 inversely correlated with invasive capability and EMT phenotype of NSCLC cells. (a) miR-149 levels in different NSCLC cell lines were measured by quantitative PCR. (b) Invasive capability of NSCLC cells was determined by invasion assay. (c) Western blot analysis of E-cadherin and vimentin in different NSCLC cell lines. (d) Relative intensity of blots in (c). (e) Transfection of miR-149 decreased the invasion of H1299 and increased the invasion of Calu3 cells (f). Data were from three independent experiments. *Compared with A549 or the control group, 𝑃<0.05, ^{* *}compared with A549 or the control group, 𝑃<0.01.

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