Cell Shape and Cardiosphere Differentiation: A Revelation by Proteomic Profiling

Figure 1

Upper Panel: Category of proteins differentially expressed in floating cardiosphere (flCS) cells and dish-attached cardiosphere (daCS) cells reported in Machida et al. [20]. Among the proteins successfully identified, about 44% were differentially expressed. Lower Panel: Comparative 2D-DIGE of CSC-21E whole cell lysates from flCS (red) and daCS (green) cultures. Proteins with similar amounts in flCS and daCS appear as yellow spots, whereas proteins differentially expressed show reddish (more abundant in flCS) or greenish (more abundant in daCS) spots. The figure was modified from Figure 3 of Machida et al. [20] with permission.