[Retracted] Exploring Drug Targets in Isoprenoid Biosynthetic Pathway for Plasmodium falciparum

Table 1

Details of genes involved in isoprenoid metabolism and their polymorphisms in P. falciparum 3D7.

Gene ID	Previous ID	Chromosome	Product description	Protein length	Nonsynonymous SNPs in all strains	Synonymous SNPs in all strains
PF3D7_0104400	PFA0225w	1	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase (LytB)	535	3	3
PF3D7_0106900	PFA0340w	1	2-C-Methyl-D-erythritol 4-phosphate cytidylyltransferase, putative (IspD)	734	6	2
PF3D7_0209300	PFB0420w	2	2-C-Methyl-D-erythritol 2,4-cyclodiphosphate synthase (IspF)	240	0	0
PF3D7_0318800	PFC0831w	3	Triosephosphate isomerase, putative	357	0	0
PF3D7_0503100	PFE0150c	5	4-Diphosphocytidyl-2c-methyl-D-erythritol kinase (CMK), putative	537	4	0
PF3D7_0508300	PFE0410w	5	Triose phosphate transporter (oTPT)	342	0	0
PF3D7_0530200	PFE1510c	5	Triose phosphate transporter (iTPT)	524	1	0
PF3D7_0623200	PFF1115w	6	Ferredoxin NADP reductase (FNR)	371	1	1
PF3D7_1022800	PF10_0221	10	4-Hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (GcpE)	824	1	0
PF3D7_1037100	PF10_0363	10	Pyruvate kinase 2 (PyKII)	745	2	1
PF3D7_1318100	MAL13P1.95	13	Ferredoxin, putative	194	2	0
PF3D7_1337200	MAL13P1.186	13	1-Deoxy-D-xylulose 5-phosphate synthase	1205	13	2
PF3D7_1439900	PF14_0378	14	Triosephosphate isomerase (TIM)	248	0	0
PF3D7_1467300	PF14_0641	14	1-Deoxy-D-xylulose 5-phosphate reductoisomerase (DOXR)	488	2	2