Review Article
Microbial Tyrosinases: Promising Enzymes for Pharmaceutical, Food Bioprocessing, and Environmental Industry
Table 1
Biochemical properties of tyrosinase.
| Sources | MW kDa/Da | Optimum temperature | Optimum pH | pI | kM (mM) | Specific activity | References |
| Aeromonas media | 58000 | 50°C | 8.0 | 4.9 | 0.64 | 34 µmol/min/mg | [55] | Beta vulgaris | 41000 | 25°C | 6.0 | NR | 0.067 | NR | [56] | Lentinula boryana | 20, 27, 47 | 50°C | 6.0 | NR | 1.9 (L-DOPA) | NR | [14] | Neurospora crassa | 46 | NR | 5.0 | NR | 0.18 | 540 µmol/min/mg | [9] | Agaricus bisporus | 112800 | 25°C | 7.0 | 4.75 | 0.36 (L-tyrosine) | 8300 µmol/min/mg | [57] | Lentinula edodes | 70, 105 | NR | 6.5 | 4.3 | 0.85 (L-DOPA) | NR | [11] | Aspergillus oryzae | 67 | 5.0–6.0 | NR | NR | NR | NR | [58] | Pycnoporus sanguineus | 45000 | 25°C | 6.5 | 4.55 | 0.9 (L-DOPA) | 3.2 µmol/min/mg | [13] | Trichoderma reesei | 43.2 | 30°C | 9.0 | 9.5 | 7.5 (L-DOPA) | NR | [47] | Streptomyces glaucescens | 3.09 | NR | NR | NR | 0.41 (L-tyrosine) | | [59] | Aspergillus nidulans | 50.48 | NR | 7.0 | NR | NR | NR | [60] | Bacillus megaterium | 31000 35000 | 50°C | 7.0 | NR | 0.075 (L-tyrosine) 0.35 (L-DOPA) | NR | [41] | Bacillus thuringiensis | NR | 75°C | 9.0 | NR | 0.563 (L-tyrosine) 0.768 (L-DOPA) | NR | [61] | Streptomyces sp. | 32000 | 35°C | 7.0 | NR | 1.25 (L-tyrosine) 4.14 (L-DOPA) | 130 µmol/min/mg | [62] | Pseudomonas putida | 36000 39000 | 30°C | 7.0 | NR | 0.23 (L-tyrosine) 0.33 (L-DOPA) | 0.375 µmol/min/mg | [20] |
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NR: not reported; DOPA: dihydroxyphenylalanine.
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