Modulatory Effects of Eschscholzia californica Alkaloids on Recombinant GABA_A Receptors

Figure 2

(a) LC UV chromatogram of Eschscholzia californica extract before fractionation. Peak identification: (1) reticuline; (2) caryachine; (3) N-methyllaurotetanine; (4) protopine; (5) californidine; (6) allocryptopine; (7) escholtzine; (8) sanguinarine; and (9) chelerythrine. (b) LC-MS trace of “NMT sample” containing 82% N-methyllaurotetanine, 10% reticuline, and 8% caryachine with traces of other alkaloids.

(a)

(b)