Differences in GPR30 Regulation by Chlorotriazine Herbicides in Human Breast Cells

Figure 1

Cell viability of MCF-7 cells treated with triazine herbicides. MCF-7 human breast cancer cells were treated with 0.1- to 10-fold concentrations of the EPA safe levels of atrazine, cyanazine, or simazine for 24 hours in reduced (a) or maintenance (b) media. Cell viability was determined by levels of reduction of resazurin to resorufin by metabolically active cells. Percent viability of cells ± standard deviation is shown, with the DMSO-treated controls normalized to 100 percent. Statistically significant changes in viability compared to the vehicle control are indicated ().

(a)

(b)