Para-Phenylenediamine Induces Apoptotic Death of Melanoma Cells and Reduces Melanoma Tumour Growth in Mice

Table 1

Effect of p-PD treatment on body weight with major organ weight in mice.

Treatment	Initial body weight (g)	Final body weight (g)	Final heart weight (g)	Final lung weight (g)	Final liver weight (g)	Final kidney weight (g)	Final spleen weight (g)
Control (vehicle only)	22 ± 0.33	25 ± 0.06	0.16 ± 0.02	0.16 ± 0.06	1.7 ± 0.04	0.35 ± 0.12	0.26 ± 0.03
Treatment dose 1	25 ± 0.09	29 ± 0.11	0.16 ± 0.04	0.13 ± 0.09	1.92 ± 0.03	0.38 ± 0.06	0.27 ± 0.03
Treatment dose 2	20 ± 0.04	24 ± 0.12	0.15 ± 0.06	0.18 ± 0.02	1.57 ± 0.08	0.32 ± 0.05	0.24 ± 0.04

Dose 1 and dose 2: p-PD 5 and 10 mg/kg/3 days, respectively.
Values are expressed as mean ± SEM ().