Research Article

Para-Phenylenediamine Induces Apoptotic Death of Melanoma Cells and Reduces Melanoma Tumour Growth in Mice

Table 2

Effect of p-PD treatment on serum biochemical parameters of mice.

TreatmentSGOT (IU/dL)SGPT (IU/dL)SALP (IU/dL)Bilirubin (mg/dL)ALT (IU/dL)AST (IU/dL)ALP (IU/dL)Urea (mg/dL)Uric acid (mg/dL)Creatinine (mg/dL)

Control (vehicle only)43 ± 11.0135 ± 5.2284 ± 8.331.0 ± 0.1246 ± 5.2395 ± 14.33286 ± 7.36155 ± 9.367 ± 9.331.0 ± 1.22
Treatment dose 141 ± 6.02 34 ± 4.1289 ± 3.63 1.0 ± 1.3247 ± 6.0397 ± 16.33296 ± 9.36157 ± 11.237 ± 14.361.0 ± 1.88
Treatment dose 245 ± 6.1437 ± 9.1186 ± 9.321.0 ± 2.3343 ± 9.5492 ± 3.63289 ± 9.36165 ± 18.336 ± 9.361.0 ± 1.22

Dose 1 and dose 2: p-PD 5 and 10 mg/kg/3 days, respectively.
Values are expressed as mean ± SEM ().