Research Article
Para-Phenylenediamine Induces Apoptotic Death of Melanoma Cells and Reduces Melanoma Tumour Growth in Mice
Table 2
Effect of p-PD treatment on serum biochemical parameters of mice.
| Treatment | SGOT (IU/dL) | SGPT (IU/dL) | SALP (IU/dL) | Bilirubin (mg/dL) | ALT (IU/dL) | AST (IU/dL) | ALP (IU/dL) | Urea (mg/dL) | Uric acid (mg/dL) | Creatinine (mg/dL) |
| Control (vehicle only) | 43 ± 11.01 | 35 ± 5.22 | 84 ± 8.33 | 1.0 ± 0.12 | 46 ± 5.23 | 95 ± 14.33 | 286 ± 7.36 | 155 ± 9.36 | 7 ± 9.33 | 1.0 ± 1.22 |
Treatment dose 1 | 41 ± 6.02 | 34 ± 4.12 | 89 ± 3.63 | 1.0 ± 1.32 | 47 ± 6.03 | 97 ± 16.33 | 296 ± 9.36 | 157 ± 11.23 | 7 ± 14.36 | 1.0 ± 1.88 |
Treatment dose 2 | 45 ± 6.14 | 37 ± 9.11 | 86 ± 9.32 | 1.0 ± 2.33 | 43 ± 9.54 | 92 ± 3.63 | 289 ± 9.36 | 165 ± 18.33 | 6 ± 9.36 | 1.0 ± 1.22 |
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Dose 1 and dose 2: p-PD 5 and 10 mg/kg/3 days, respectively.
Values are expressed as mean ± SEM ().
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