Biochemistry Research International

Research Article

The Protective Effect of Naringenin-Oxime on Cisplatin-Induced Toxicity in Rats

Table 3

Effects of cisplatin (7 mg/kg), naringenin oxime (20 mg/kg) (NOX₂₀), Cis + NOX₂₀, and Cis + NOX₄₀ on paraoxonase (PON) and arylesterase (ARYL) in serum and liver of rats.


	PON		ARYL
	Serum	Liver	Serum	Liver

Control	138,3 ± 29,	239,9 ± 46,	68,5 ± 4,	111,4 ± 21,
Cis	114,0 ± 21,	126,9 ± 23,	59,9 ± 3,	72,3 ± 19,
Cis + NOX₂₀	107,0 ± 51,5	157,1 ± 33,1	63,7 ± 12,	87,8 ± 21,9
Cis + NOX₄₀	130,9 ± 16,	198,7 ± 25,	69,7 ± 10,	103,0 ± 13,9
NOX₂₀	111,9 ± 45,	236,4 ± 34,	67,2 ± 5,	107,8 ± 6,2
value	0,000	0,000	0,000	0,001

Values are given as the means ± SD. There were no significant differences between the cis and control groups in terms of any parameter (). , compared with the control group. , groups in which Cis and NOX are treated together compared with the Cis group.