Biotechnology Research International

Research Article

Optimization of the Nutritional Parameters for Enhanced Production of B. subtilis SPB1 Biosurfactant in Submerged Culture Using Response Surface Methodology

Table 2

Plackett-Burman experimental design for 11 variables and the corresponding responses in g/L.
Factors (coded)
Exp N° Biosurfactant yield (g/ L)
1 1 1−1 1 1 1−1−1−1 1−1 2.06
2−1 1 1−1 1 1 1−1−1−1 11.61
3 1−1 1 1−1 1 1 1−1−1−12.22
4−1 1−1 1 1−1 1 1 1−1−11.8
5−1−1 1−1 1 1−1 1 1 1−10.7
6−1−1−1 1−1 1 1−1 1 1 10.7
7 1−1−1−1 1−1 1 1−1 1 11.8
8 1 1−1−1−1 1−1 1 1−1 11.7
9 1 1 1−1−1−1 1−1 1 1−11.9
10−1 1 1 1−1−1−1 1−1 1 10.9
11 1−1 1 1 1−1−1−11−1 10.8
12−1−1−1−1−1−1−1−1−1−1−10.3
13000000000001.52
14000000000001.49
15000000000001.59
16000000000001.54
17000000000001.48