Graph-Theoretic Models of Mutations in the Nucleotide Binding Domain 1 of the Cystic Fibrosis Transmembrane Conductance Regulator

Table 2

Combinatorial descriptors.

	Δ∑𝐻	𝛿∑𝐻	Δ∑𝑃	𝛿∑𝑃	𝛿∑𝐶/deg	𝜔𝑒/𝑣	∑𝑒/𝑣	𝑃^𝜔3	𝐶𝛾	Δ𝐼^𝑑𝑝
WT	16.7	−22.5	14.754	7.57	6.857	6.447	21.602	17	36	14.855
ΔI507	12.2	−22.0	14.568	7.38	6.857	6.030	21.390	17	36	14.521
ΔF508	13.9	−22.0	14.464	7.28	6.307	6.030	21.390	17	36	14.455
G542A	16.7	−22.0	14.800	7.62	6.857	6.447	21.245	11	36	15.355
S549N	16.7	−22.0	14.826	7.64	6.857	6.447	21.387	17	36	14.730
S549I	16.7	−22.0	14.878	7.69	6.857	6.447	21.459	11	36	15.355
S549R	16.7	−22.0	14.983	7.80	6.857	6.447	21.459	17	36	14.730
G551D	14.0	−24.7	14.754	7.68	6.857	6.447	22.102	17	12	14.855
R560T	20.5	−18.2	14.754	7.39	6.857	6.447	22.102	17	36	14.855