The Impact of a Pulmonary-Artery-Catheter-Based Protocol on Fluid and Catecholamine Administration in Early Sepsis

Table 2

Primary outcome variables: fluid balance and use of vasoactive drugs.

	PAC (𝑛=70)	Control (𝑛=70)	P value
Fluid balance day 0–4 hours (L)	2.0±1.4	1.9±1.4	0.79
Fluid balance day 1	6.1±2.6	3.8±2.4	0.000
Fluid balance day 2	3.7±2.0	4.8±2.3	0.002
Fluid balance day 3	1.6±1.9	3.2±2.4	0.000
Fluid balance day 4	−0.1±2.1	1.4±2.6	0.000
Fluid balance day 5	−0.3±1.7	0.1±2.2	0.13
Fluid balance day 6	−0.7±1.4	−0.5±2.1	0.26
Fluid balance day 7	−0.7±1.6	0.1±2.2	0.01
Fluid balance day 1–7	9.4±7.4	13 ± 7.6	0.002
Maximum dose norepinephrine (μg/kg/min, n)	0.12 (0.03–0.19), 59	0.02 (0–0.17), 39	0.000
Maximum dose dopamine (μg/kg/min, n)	7.02 (4.7–9.8), 65	7.7 (4.7–9.6), 66	0.79

PAC: pulmonary artery catheter. Data are presented as mean ± SD, median (IQR) or as numbers.