Increased Extravascular Lung Water Reduces the Efficacy of Alveolar Recruitment Maneuver in Acute Respiratory Distress Syndrome

Table 2

Arterial blood gases, hemodynamics and parameters of mechanical ventilation in responders and nonresponders to lung recruitment maneuver.

Parameter	Responders (𝑛=5)	Nonresponders (𝑛=12)	P
PaO2/FiO2 baseline, mm Hg	127 ± 50	155 ± 45	0.27
PaO2/FiO2 after RM, mm Hg	158 (136–311)	152 (116–161)	0.29
PaO2/FiO2 stability of RM, mm Hg	152 ± 63	141 ± 44	0.71
PaCO2 baseline, mm Hg	45 ± 8	45 ± 8	0.98
PaCO2 after RM, mm Hg	45 ± 12	49 ± 8	0.25
PaCO2 stability of RM, mm Hg	43 ± 7	48 ± 8	0.27
CI, L/min/m^2	3.17±0.90	3.84±1.29	0.31
MAP, mm Hg	71 ± 7	96 ± 26	0.06
SVRI, dyn sec cm^−5/m^2	1717 (1089–1994)	1662 (1285–2271)	0.46
HR, beat/min	95 ± 8	112 ± 29	0.22
GEDVI, mL/m^2	702 ± 136	695 ± 130	0.92
EVLWI, mL/kg	11.6±5.5	13.1±4.4	0.55
FiO2, %	50 (50–80)	50 (50–60)	0.51
Tidal volume, mL	494 ± 58	444 ± 55	0.14
Minute ventilation, L/min	11.6±4.2	10.3±1.6	0.43
Dynamic respiratory compliance, mL/cm H2O	29 (26–62)	28 (24–35)	0.39

Data are presented as mean ± standard deviation or median (25th–75th percentile).
RM: recruitment maneuver; CI: cardiac index; MAP: mean arterial pressure; SVRI: systemic vascular resistance index; HR: heart rate; GEDVI: global end-diastolic volume index; EVLWI: extravascular lung water index.