Mechanical Ventilation and the Titer of Antibodies as Risk Factors for the Development of Transfusion-Related Lung Injury

Figure 1

(a) Total protein in the bronchoalveolar lavage fluid (BALF) (𝑛=12 per group), (b) wet-to-dry ratio of the lungs (𝑛=6 per group), (c) neutrophil influx in bronchoalveolar lavage fluid (𝑛=12 per group), and (d) histopathological examination of lung tissue (𝑛=6 per group). Low V_T= mice ventilated with a tidal volume of 7.5 mL/kg; high V_T= mice ventilated with a tidal volume of 15 mL/kg. Dose of MHC-I antibodies infused 0.5, 2.0, and 4.5 mg/kg. Controls received vehicle. BALF = bronchoalveolar lavage fluid. ^∗𝑃<0.05, ^∗∗𝑃<0.01.

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