Comparison of Goal-Directed Hemodynamic Optimization Using Pulmonary Artery Catheter and Transpulmonary Thermodilution in Combined Valve Repair: A Randomized Clinical Trial
Table 2
Changes in hemodynamic parameters in the study groups.
Group
Before surgery
End of surgery
2 hrs
6 hrs
12 hrs
18 hrs
24 hrs
CVP, mm Hg
TTD group
12 ± 4
16 ± 4†
11 ± 4
12 ± 4*
11 ± 5
13 ± 5*
14 ± 4
PAC group
13 ± 4
16 ± 3†
12 ± 4
10 ± 3†
10 ± 4†
11 ± 3†
12 ± 4
PAOP, mm Hg
PAC group
19 ± 7
18 ± 6
15 ± 6†
13 ± 4†
12 ± 5†
15 ± 6†
16 ± 3
GEDVI, mL m−2
TTD group
757 ± 191
707 ± 63
719 ± 150
747 ± 106
815 ± 203†
824 ± 214†
839 ± 205†
SVV, %
TTD group
8 ± 5
13 ± 5
13 ± 6
13 ± 5
14 ± 7
15 ± 5†
16 ± 6†
EVLWI, mL kg−1
TTD group
12 ± 4
11 ± 2†
10 ± 3†
9 ± 2†
10 ± 3
10 ± 3†
10 ± 2
MAP, mm Hg
TTD group
73 ± 15
72 ± 13*
74 ± 15
71 ± 8
80 ± 11
87 ± 16†
88 ± 15†
PAC group
72 ± 17
66 ± 8
74 ± 11
71 ± 11
80 ± 11
87 ± 12†
82 ± 21
SVRI, dyne·sec−1 cm−5 m−2
TTD group
2732 ± 738
1913 ± 564*†
2093 ± 711†
1730 ± 443†
1948 ± 534*†
2216 ± 692†
2073 ± 517†
PAC group
2610 ± 1039
1466 ± 411†
1962 ± 644†
2030 ± 618†
2345 ± 716
2493 ± 626
2286 ± 581
HR, min−1
TTD group
65 ± 12
82 ± 22†
78 ± 11†
74 ±11†
75 ± 15†
77 ± 14†
74 ± 11†
PAC group
71 ± 14
79 ± 12†
78 ± 11†
79 ± 14†
75 ± 15
77 ± 13
80 ± 13†
TTD: transpulmonary thermodilution; PAC: pulmonary artery catheter; CVP: central venous pressure; PAOP: pulmonary artery occlusion pressure; GEDVI: global end-diastolic volume index; EVLWI: extravascular lung water index; MAP: mean arterial pressure; SVRI: systemic vascular resistance index; HR: heart rate.
*
between the groups; † within the group compared with the preoperative value. Data are presented as mean ± SD.
