Comparison of Goal-Directed Hemodynamic Optimization Using Pulmonary Artery Catheter and Transpulmonary Thermodilution in Combined Valve Repair: A Randomized Clinical Trial

Table 3

Changes in oxygenation and laboratory parameters in the study groups.

Parameter	Group	Before surgery	End of surgery	2 hrs	6 hrs	12 hrs	18 hrs	24 hrs
PaO2/FiO2, mm Hg	TTD group	330 ± 104	269 ± 129^†	322 ± 124	329 ± 102	337 ± 137	311 ± 114	291 ± 82
	PAC group	279 ± 114	234 ± 89	286 ± 96	325 ± 87	324 ± 76	309 ± 101	310 ± 134
ScvO2, %	TTD group	73 ± 10	71 ± 15	69 ± 10	66 ± 14	69 ± 11*	65 ± 14^†	66 ± 8^†
	PAC group	70 ± 9	78 ± 10^†	74 ± 10	75 ± 10	75 ± 14^†	67 ± 14	65 ± 9
pH	TTD group	7.39±0.04	7.34±0.01^†	7.35±0.04^†	7.34±0.07^†	7.35±0.07^†	7.38±0.05	7.41±0.05^†
	PAC group	7.38±0.05	7.34±0.05^†	7.33±0.06^†	7.38±0.05	7.39±0.05	7.42±0.05^†	7.43±0.04^†
Lactate, mmol L^−1	TTD group	0.9±0.3	2.8±1.0^†	2.2±1.1^†	3.3±2.1^†	3.6±2.2^†	2.5±1.6^†	2.2±1.1^†
	PAC group	0.9±0.3	3.0±0.9^†	2.5±1.2^†	3.5±2.1^†	4.0±2.6^†	2.5±1.2^†	2.1±0.6^†
Hb, g dL^−1	TTD group	12.7±1.9	9.0±1.4^†	10.1±2.1^†	10.5±1.7^†	11.1±1.3^†	11.0±1.5^†	10.9±1.3^†
	PAC group	11.7±1.4	8.4±1.2^†	9.6±2.0^†	10.5±1.4^†	10.7±1.4^†	10.6±1.2^†	10.6±1.7^†
Glucose, mmol L^−1	TTD group	5.8±2.0	7.3±3.2	7.6±3.7	11.9±4.1^†	12.0±6.9^†	8.7±2.2^†	7.8±3.1
	PAC group	5.8±1.7	8.5±4.3^†	8.4±3.4^†	10.3±3.9^†	12.8±4.7^†	9.3±3.7^†	8.6±5.5^†

TTD: transpulmonary thermodilution; PAC: pulmonary artery catheter; PaO₂: partial arterial oxygen pressure; FiO₂: fraction of inspired oxygen; ScvO₂: central venous oxygen saturation; Hb: hemoglobin.
* 𝑃<0.05 between the groups; ^†𝑃<0.05 within the group compared with the preoperative value. Data are presented as mean ± SD.