Impact of Enzymatic Degradation of the Endothelial Glycocalyx on Vascular Permeability in an Awake Hamster Model

Table 1

Hemodymanical parameters and hematology.

	Baseline		60 minutes		120 minutes
	Enzyme	Control	Enzyme	Control	Enzyme	Control
MAP	114 (5)	111 (6)	109 (5)	104 (9)	106 (9)	99 (5)^*
HR	459 (16)	468 (17)	455 (22)	473 (18)	454 (16)	448 (16)^*
Hct	49 (2)	50 (2)	47 (2)	47 (2)	45 (2)^**	45 (2)^***
Ph	7.37 (0.03)	7.35 (0.04)	7.35 (0.04)	7.32 (0.04)	7.35 (0.02)	7.32 (0.03)
PaO2	56.7 (9.9)	54.4 (5.7)	61.2 (5.9)	59.5 (8.9)	57.1 (10.9)	59.2 (7.4)
PaCO2	56.6 (7.5)	59.7 (3.89)	56.1 (7.6)	61.3 (6.6)	55.7 (5.2)	59.2 (2.7)
BE	6.8 (2.8)	6.9 (2.1)	4.4 (1.6)	4.7 (2.3)	4.4 (1.6)	3.9 (2.0)

Values are given as mean and standard deviation. MAP: mean arterial pressure, HR: heart rate, Hct: hematocrit, BE: base excess. Significant differences were seen within the groups from baseline to 120 minutes (MAP and Hct) and from 60 to 120 minutes in the control group (HR). ^*𝑃<0.05, ^**𝑃<0.01, ^***𝑃<0.001.