Table 1: Patient characteristics: Trauma patients with acute kidney injury with continuous renal replacement therapy (CRRT) grouped with and without rhabdomyolysis ( ).

Total ( )Rhabdomyolysis ( )Not rhabdomyolysis ( )P value

Demographic data
 Age (years)48 (30–65)35 (23–51)57 (44–68)0.01
 Male gender31 (86)17 (100)14 (74)0.02
 SAPS II score41 (32–48)38 (31–48)41 (32–49)0.90
 ISS score34 (26–47)43 (17–50)34 (27–41)0.24
Indication for CRRT
 Fluid overload19 (53)8 (47)11 (58)0.52
 Hyperkalemia20 (56)9 (53)11 (58)0.77
 Acidosis15 (42)3 (18)12 (63)0.01
 Uremia9 (25)4 (24)5 (26)0.85
 Rhabdomyolysis17 (47)17 (100)0 (0) <0.01
Kidney function at start of CRRT
 Diuresis (mL/day)536 (256–1692)522 (252–2060)550 (255–1410)0.80
 Serum potassium (mmol/L)5.0 (4.2–5.5)4.4 (4.0–5.7)5.1 (4.8–5.5)0.20
 Serum urea (mmol/L)17.8 (12.5–28.4)13.6 (10.6–25.0)22.2 (16.3–29.8)0.07
 Serum creatinine (μmol/L)249 (204–376)247 (198–483)269 (215–361)0.95
 Serum creatine kinase (U/L)4638 (460–24414)24415 (9660–45740)603 (135–2152) <0.01
CRRT performance data
 Median daily CRRT duration (hours)18.6 (14.9–21.3)16.3 (12.4–20.0)19.7 (15.6–21.8)0.19
 Median Δurea-0.05 (−0.12–0.09)-0.06 (−0.19–0.03)-0.05 (−0.08–0.11)0.20
 Median Δcreatinine0.05 (−0.04–0.17)0.03 (−0.17–0.15)0.12 (0.01–0.17)0.21
 Filter clotting pauses68 (54)36 (55)32 (53)0.90
 Therapeutic pauses32 (25)25 (38)7 (12) <0.01
 Catheter-related pauses12 (10)3 (5)9 (15)0.05
 Filter timeout pauses7 (6)1 (2)6 (10)0.04
 Diagnostic pauses7 (6)5 (8)2 (3)0.30
Outcome
 Dialysis-dependent 3 months0 (0)0 (0)0 (0)n.c.
 Dialysis-dependent 1 year0 (0)0 (0)0 (0)n.c.
 Mortality 3 months11 (31)3 (18)8 (42)0.11
 Mortality 1 year13 (36)4 (24)9 (47)0.14

Categorical data are presented as number (percent) and compared using Pearson chi-square test. Continuous data are expressed as median (interquartile range) and are compared using 2-tailed Mann-Whitney U test. SAPS II: simplified acute physiology score II. ISS: injury severity score. n.c.: not calculated. See text for other definitions.