Research Article

The Extent of Ventilator-Induced Lung Injury in Mice Partly Depends on Duration of Mechanical Ventilation

Figure 1

Hemodynamic parameters. Systolic blood pressures, heart rates, and peripheral oxygen saturation (SpO2) remained stable throughout 5 hours ((a)–(c)) and 12 hours ((d)–(f)) of mechanical ventilation (MV). Data are presented as median (IQR) of 12–15 ((a)-(b), (d)-(e)), or 3–6 ((c), (f)) mice per group (circle = LVT; square = HVT). LVT, HVT = LVT/PEEP or HVT/ZEEP ventilator settings.
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(a)
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(b)
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(c)
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(d)
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(e)
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(f)