Central Venous-to-Arterial CO₂ Gap Is a Useful Parameter in Monitoring Hypovolemia-Caused Altered Oxygen Balance: Animal Study

Table 4

Changes in microcirculation.

		𝑇0	𝑇1	𝑇2	𝑇3	𝑇4	𝑇5
Ba-PCO2 (mmHg)	HG	24 ± 8	35 ± 16^*‡	35 ± 17	36 ± 13*	33 ± 13*	37 ± 16*
	SG	19 ± 5	22 ± 9	20 ± 6	22 ± 11	22 ± 10	20 ± 8
Ga-PCO2 (mmHg)	HG	40 ± 12	43 ± 14	42 ± 14	39 ± 14	36 ± 10	37 ± 11
	SG	36 ± 22	37 ± 24	34 ± 21	32 ± 21	34 ± 20	32 ± 18
CPR (%)	HG	82 ± 15	—	53 ± 11^*‡#	—	—	45 ± 16^*‡#
	SG	91 ± 50		81 ± 80			83 ± 70
RBCV (μm/s)	HG	887 ± 141	—	509 ± 120^*‡#	—	—	463 ± 209^*#
	SG	1054 ± 141		848 ± 194			963 ± 51
BigET (fmol/mL)	HG	1.44 ± 0.53	—	1.97 ± 0.84^*‡	—	—	2.29 ± 0.89^*#
	SG	1.36 ± 0.93		1.49 ± 1.27			0.98 ± 0.92*

Ba-PCO₂: small bowel-to-arterial carbon dioxide difference; Ga-PCO₂: gastric-to-arterial carbon dioxide difference; CPR: capillary perfusion rate; RBCV: red blood cell velocity; BigET: big endothelin. 𝑇₀: baseline measurement; 𝑇₁--𝑇₅: five intervals. *𝑝<.05 as compared to 𝑇₁, ^‡𝑝<.05 as compared to the previous value, GLM repeated measures ANOVA; ^#𝑝<.05 HG versus SG, Mann-Whitney 𝑈-test with Bonferroni correction.