Is Vitamin D Insufficiency Associated with Mortality of Critically Ill Patients?
Table 2
Comparison of patients who were vitamin D insufficient and sufficient.
Variable
Vitamin D insufficient (<20 ng/mL) ()
Vitamin D sufficient (≥20 ng/mL) ()
value
Age (years)
66 [58–78]
65 [42–77]
0.184
Male gender
72 (52%)
41 (66%)
0.06
Length of ICU stay (days)
9 [5–14]
8 [5–13]
0.355
On admission
SOFA score
8 [6–11]
6 [4–9]
0.005
APACHE II score
24 [19–28]
19 [16–25]
0.006
25(OH)D level (ng/mL)
10 [6–16]
34 [28–46]
0.001
Leukocytes (/mm3)
12300 [8200–17500]
11150 [5370–14980]
0.02
Procalsitonin level (ng/mL)
3.7 [1.2–25.4]
1.5 [0.5–7.8]
0.044
Calcium (mg/dL)
7.8 [7.2–8.4]
8.2 [7.4–9]
0.006
Calcium, ionized (mmol/L)
1.12 [1–1.23]
1.22 [1.1–1.3]
0.001
Albumin (mg/dL)
2.6 [2.1–3.1]
2.8 [2.5–3.3]
0.010
Sepsis/septic shock
57 (41%)
15 (24.2%)
0.026
Invasive mechanical ventilation
69 (50%)
19 (31%)
0.012
Organ dysfunction
116 (84%)
44 (71%)
0.042
During ICU
Invasive blood pressure monitoring
85 (64%)
26 (45%)
0.014
Central venous pressure monitoring
91 (69%)
28 (48%)
0.007
RRT (hemodialysis)
55 (40%)
14 (23%)
0.025
Nosocomial infections
54 (39%)
17 (27%)
0.117
ICU mortality
60 (43%)
16 (26%)
0.027
Values are presented as median [interquartile range] or (%); APACHE: acute physiology and chronic health evaluation, SOFA: sequential organ failure assessment, and ICU: intensive care unit.
